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An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis

The Om-toxins are short peptides (23–27 amino acids) purified from the venom of the scorpion Opisthacanthus madagascariensis. Their pharmacological targets are thought to be potassium channels. Like Csα/β (cystine-stabilized α/β) toxins, the Om-toxins alter the electrophysiological properties of the...

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Detalhes bibliográficos
Main Authors: Chagot, Benjamin, Pimentel, Cyril, Dai, Li, Pil, Joost, Tytgat, Jan, Nakajima, Terumi, Corzo, Gerardo, Darbon, Hervé, Ferrat, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186715/
https://ncbi.nlm.nih.gov/pubmed/15631621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041705
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