Molecular, functional and structural properties of the prolyl oligopeptidase of Trypanosoma cruzi (POP Tc80), which is required for parasite entry into mammalian cells

We have demonstrated that the 80 kDa POP Tc80 (prolyl oligopeptidase of Trypanosoma cruzi) is involved in the process of cell invasion, since specific inhibitors block parasite entry into non-phagocytic mammalian host cells. In contrast with other POPs, POP Tc80 is capable of hydrolysing large subst...

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Hlavní autoři: Bastos, Izabela M. D., Grellier, Philippe, Martins, Natalia F., Cadavid-Restrepo, Gloria, de Souza-Ault, Marian R., Augustyns, Koen, Teixeira, Antonio R. L., Schrével, Joseph, Maigret, Bernard, da Silveira, José F., Santana, Jaime M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2005
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186690/
https://ncbi.nlm.nih.gov/pubmed/15581422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041049
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