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Utilization of endogenous and exogenous sources of substrate for cholesterol biosynthesis by isolated hepatocytes

The rates of cholesterol biosynthesis in isolated rat hepatocytes were determined by using a method based on measurement of the rate of formation of desmosterol (cholesta-5,24-dien-3β-ol), which accumulates during inhibition of cholesterogenesis by the drug triparanol. Incubation of cells from norma...

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Detalhes bibliográficos
Main Authors: Gibbons, Geoffrey F., Pullinger, Clive R.
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186364/
https://ncbi.nlm.nih.gov/pubmed/426772
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