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The growing pre-mRNA recruits actin and chromatin-modifying factors to transcriptionally active genes

In the dipteran Chironomus tentans, actin binds to hrp65, a nuclear protein associated with mRNP complexes. Disruption of the actin–hrp65 interaction in vivo by the competing peptide 65-2CTS reduces transcription drastically, which suggests that the actin–hrp65 interaction is required for transcript...

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Detalhes bibliográficos
Main Authors: Sjölinder, Mikael, Björk, Petra, Söderberg, Emilia, Sabri, Nafiseh, Östlund Farrants, Ann-Kristin, Visa, Neus
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186187/
https://ncbi.nlm.nih.gov/pubmed/16103215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.339405
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