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The growing pre-mRNA recruits actin and chromatin-modifying factors to transcriptionally active genes
In the dipteran Chironomus tentans, actin binds to hrp65, a nuclear protein associated with mRNP complexes. Disruption of the actin–hrp65 interaction in vivo by the competing peptide 65-2CTS reduces transcription drastically, which suggests that the actin–hrp65 interaction is required for transcript...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1186187/ https://ncbi.nlm.nih.gov/pubmed/16103215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.339405 |
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