Učitavanje...
4E-BP functions as a metabolic brake used under stress conditions but not during normal growth
4E-BP is an important regulator of overall translation levels in cells. By binding eIF4E, 4E-BP impairs recruitment of the 40S ribosomal subunit to the cap structure present at the 5′-end of all eukaryotic cellular mRNAs. 4E-BP activity is controlled by TOR (Target of Rapamycin). 4E-BP has been stud...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2005
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1186183/ https://ncbi.nlm.nih.gov/pubmed/16103212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.341505 |
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