The effect of sugars on (pro)insulin biosynthesis

Rates of incorporation of [4,5-(3)H]leucine into insulin plus proinsulin, designated `(pro)insulin', and total protein in rat pancreatic islets were measured. Glucose stimulates rates of total protein and (pro)insulin biosynthesis, but (pro)insulin biosynthesis is stimulated preferentially. Man...

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Bibliographic Details
Main Authors: Ashcroft, Stephen J. H., Bunce, Judy, Lowry, Martin, Hansen, Svend E., Hedeskov, Carl J.
Format: Artigo
Language:Inglês
Published: 1978
Subjects:
Cellular Interactions and Control Processes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1185943/
https://ncbi.nlm.nih.gov/pubmed/361036
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