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Resistance to the aminoglycoside antibiotic neamine in Escherichia coli. A new mutant whose NeaR phenotype results from the cumulative effects of two distinct mutations.

A spontaneous mutant of Escherichia coli (strain AB2847), selected for resistance to the aminoglycoside antibiotic neamine, shows severe restriction of amber suppressors in vivo. Ribosomes isolated from the mutant exhibit only low misreading in vitro in the presence of the antibiotic. Genetic and bi...

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Autors principals: Delcuve, G, Cabezón, T, Herzog, A, Cannon, M, Bollen, A
Format: Artigo
Idioma:Inglês
Publicat: 1978
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1185878/
https://ncbi.nlm.nih.gov/pubmed/358966
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