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Effect of heparin on thrombin inactivation by antithrombin-III.

The inactivation of thrombin by heat and by its physiological inhibitor, antithrombin-III, shows quite different dependence on heparin concentration. Heparin at 250 microgram/ml protects thrombin against heat inactivation, and thrombin behaves heterogeneously in this reaction. In the absence of hepa...

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Bibliographic Details
Main Authors: Machovich, R, Arányi, P
Format: Artigo
Language:Inglês
Published: 1978
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1185853/
https://ncbi.nlm.nih.gov/pubmed/708377
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