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Kinetic and mechanistic studies of methylated liver alcohol dehydrogenase.
Reductive methylation of lysine residues activates liver alcohol dehydrogenase in the oxidation of primary alcohols, but decreases the activity of the enzyme towards secondary alcohols. The modification also desensitizes the dehydrogenase to substrate inhibition at high alcohol concentrations. Stead...
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Autor principal: | |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1978
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1185802/ https://ncbi.nlm.nih.gov/pubmed/697732 |
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