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The simultaneous release by bone explants in culture and the parallel activation of procollagenase and of a latent neutral proteinase that degrades cartilage proteoglycans and denatured collagen.

1. A latent neutral proteinase was found in culture media of mouse bone explants. Its accumulation during the cultures is closely parallel to that of procollagenase; both require the presence of heparin in the media. 2. Latent neutral proteinase was activated by several treatments of the media known...

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Detalhes bibliográficos
Main Authors: Vaes, G, Eeckhout, Y, Lenaers-Claeys, G, François-Gillet, C, Druetz, J E
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1185692/
https://ncbi.nlm.nih.gov/pubmed/208518
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