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Determination of the relative amounts of Gag and Pol proteins in foamy virus particles

We determined the relative ratios of Gag and Pol molecules in highly purified virions of spumaretroviruses or foamy viruses (FVs) using monoclonal antibodies and bacterially expressed reference proteins. We found that the cleaved p68(Gag )moiety dominates in infectious FVs. Furthermore, approximate...

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Bibliografiske detaljer
Main Authors: Cartellieri, Marc, Rudolph, Wolfram, Herchenröder, Ottmar, Lindemann, Dirk, Rethwilm, Axel
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1185564/
https://ncbi.nlm.nih.gov/pubmed/16004609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-2-44
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