High-mobility-group A1 (HMGA1) proteins down-regulate the expression of the recombination activating gene 2 (RAG2)

HMGA1 (high-mobility-group A1) proteins are architectural transcription factors that are found overexpressed in embryogenesis and malignant tumours. We have shown previously that they have a role in lymphopoiesis, since the loss of HMGA1 expression leads to an impairment of T-cell development and to...

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Hlavní autoři: Battista, Sabrina, Fedele, Monica, Hoyos, Josefina Martinez, Pentimalli, Francesca, Pierantoni, Giovanna Maria, Visone, Rosa, De Martino, Ivana, Croce, Carlo Maria, Fusco, Alfredo
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2005
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184541/
https://ncbi.nlm.nih.gov/pubmed/15713121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041607
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