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Influence of proline position upon the ion channel activity of alamethicin.

Alamethicin, a 20-residue peptaibol, induces voltage-dependent ion channels in lipid bilayers according to the barrel-stave model. To study relationships between the proline-14-induced kink region and the channel-forming behavior of the peptide, a set of alamethicin analogs with proline incorporated...

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Autors principals: Kaduk, C, Duclohier, H, Dathe, M, Wenschuh, H, Beyermann, M, Molle, G, Bienert, M
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184409/
https://ncbi.nlm.nih.gov/pubmed/9129817
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