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A study of the role of the reactive thiol group of rabbit muscle creatine kinase with a chromophoric reporter group.

Substrate- and ligand-induced conformational changes were studied in a series of thiol-modified derivatives of rabbit muscle creatine kinase that retained different amounts of enzymic activity. The results indicate that the 'reactive' thiol group of the enzyme is required for the conformat...

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Detalhes bibliográficos
Main Authors: Keighren, M A, Price, N C
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184157/
https://ncbi.nlm.nih.gov/pubmed/646820
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