The fate of bilirubin-IXalpha glucuronide in cholestasis and during storage in vitro. Intramolecular rearrangement to positional isomers of glucuronic acid.

1. In aqueous solution above pH7 bilirubin-IXalpha 1-O-acylglucuronide rapidly isomerizes to the non-C-1 glucuronides by sequential migration of the bilirubin acyl group from position 1 to positions 2, 3 and 4 of the sugar moiety. The transformations are enhanced by increasing the pH. Compared with...

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Hlavní autoři: Blanckaert, N, Compernolle, F, Leroy, P, Van Houtte, R, Fevery, J, Heirwegh, K P
Médium: Artigo
Jazyk:Inglês
Vydáno: 1978
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184149/
https://ncbi.nlm.nih.gov/pubmed/417725
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