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Cross down-regulation of leptin and insulin receptor expression and signalling in a human neuronal cell line
Leptin and insulin are major signals to the hypothalamus to regulate energy homoeostasis and body adiposity. IR (insulin receptors) and leptin receptors (long isoform, ObRb) share a number of signalling cascades, such as JAK2/STAT-3 (Janus kinase 2/signal transduction and activator of transcription...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Portland Press Ltd.
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1183474/ https://ncbi.nlm.nih.gov/pubmed/15715521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041621 |
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