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Curved DNA molecules migrate anomalously slowly in free solution

The electrophoretic mobility of a curved DNA restriction fragment taken from the VP1 gene in the SV40 minichromosome has been measured in polyacrylamide gels and free solution, using capillary electrophoresis. The 199 bp restriction fragment has an apparent bend angle of 46 ± 2° located at SV40 sequ...

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Autores principales: Stellwagen, Earle, Lu, Yongjun, Stellwagen, Nancy C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1183105/
https://ncbi.nlm.nih.gov/pubmed/16085753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki748
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