Regulation of the Interaction between Glycogen Synthase Kinase 3 and the Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen

The Kaposi's sarcoma-associated herpesvirus (KSHV)-encoded latency-associated nuclear antigen (LANA) protein stabilizes β-catenin by the novel mechanism of binding to the negative regulator, glycogen synthase kinase 3 (GSK-3), and depleting cytoplasmic GSK-3 levels. The two domains of LANA requ...

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Main Authors: Fujimuro, Masahiro, Liu, Jianyong, Zhu, Jian, Yokosawa, Hideyoshi, Hayward, S. Diane
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182668/
https://ncbi.nlm.nih.gov/pubmed/16051835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10429-10441.2005
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