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Capsid Processing Requirements for Abrogation of Fv1 and Ref1 Restriction

Murine leukemia virus is restricted in mouse cells lines by a host factor known as Fv1 and in human cell lines by Ref1. Genetic evidence indicates that these restriction factors target the virus capsid (CA) protein. Restriction can be overcome by adding virus at a high multiplicity of infection, ind...

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Detalhes bibliográficos
Main Authors: Dodding, Mark P., Bock, Michael, Yap, Melvyn W., Stoye, Jonathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182663/
https://ncbi.nlm.nih.gov/pubmed/16051849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10571-10577.2005
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