Epstein-Barr Virus Nuclear Protein 3A Domains Essential for Growth of Lymphoblasts: Transcriptional Regulation through RBP-Jκ/CBF1 Is Critical

Experimental reverse genetic replacement of Epstein-Barr virus nuclear antigen 3A (EBNA3A) with a conditional mutant EBNA3A revealed that EBNA3A is critical for continued lymphoblastoid cell (LCL) growth. Wild-type (wt) EBNA3A expressed in the LCLs specifically sustained growth under nonpermissive c...

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Detalhes bibliográficos
Main Authors: Maruo, Seiji, Johannsen, Eric, Illanes, Diego, Cooper, Andrew, Zhao, Bo, Kieff, Elliott
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182629/
https://ncbi.nlm.nih.gov/pubmed/16051810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10171-10179.2005
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