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Advanced glycation endproduct-induced aging of the retinal pigment epithelium and choroid: A comprehensive transcriptional response

Advanced glycation endproduct (AGE) formation is a trigger for the onset of age-related disease. To evaluate AGE-induced change in the ocular fundus, 5-mo-old C57BL/6 mice were given low-dose d-galactose (d-gal) for 8 wk and evaluated by AGE fluorescence, electroretinography (ERG), electron microsco...

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Autors principals: Tian, Jane, Ishibashi, Kazuki, Ishibashi, Kazuko, Reiser, Karen, Grebe, Rhonda, Biswal, Shyam, Gehlbach, Peter, Handa, James T.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182551/
https://ncbi.nlm.nih.gov/pubmed/16081535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504759102
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