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Docosahexaenoic acid: A positive modulator of Akt signaling in neuronal survival

Phosphatidylinositol 3-kinase [PI (3)K]/Akt signaling is a critical pathway in cell survival. Here, we demonstrate a mechanism where membrane alteration by the n-3 fatty acid status affects Akt signaling, impacting neuronal survival. Docosahexaenoic acid (DHA), an n-3 polyunsaturated fatty acid high...

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Bibliografiske detaljer
Main Authors: Akbar, Mohammed, Calderon, Frances, Wen, Zhiming, Kim, Hee-Yong
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182431/
https://ncbi.nlm.nih.gov/pubmed/16040805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502903102
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