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Optimization of the Lactococcus lactis nisin-controlled gene expression system NICE for industrial applications

BACKGROUND: The nisin-controlled gene expression system NICE of Lactococcus lactis is one of the most widely used expression systems in Gram-positive bacteria. Despite its widespread use, no optimization of the culture conditions and nisin induction has been carried out to obtain maximum yields. As...

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Detalhes bibliográficos
Main Authors: Mierau, Igor, Olieman, Kees, Mond, James, Smid, Eddy J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182390/
https://ncbi.nlm.nih.gov/pubmed/15921537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-4-16
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