Polymorphisms in the Sclerosteosis/van Buchem Disease Gene (SOST) Region Are Associated with Bone-Mineral Density in Elderly Whites

Osteoporosis has a strong genetic component, but the genes involved are poorly defined. We studied whether the sclerosteosis/van Buchem disease gene (SOST) is an osteoporosis-risk gene by examining its association with bone-mineral density (BMD). Mutations in SOST result in sclerosteosis, and altera...

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Autori principali: Uitterlinden, Andre G., Arp, Pascal P., Paeper, Bryan W., Charmley, Patrick, Proll, Sean, Rivadeneira, Fernando, Fang, Yue, van Meurs, Joyce B. J., Britschgi, Theresa B., Latham, John A., Schatzman, Randall C., Pols, Huibert A. P., Brunkow, Mary E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Human Genetics 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182139/
https://ncbi.nlm.nih.gov/pubmed/15514891
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