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Offspring Gender Ratio and the Rate of Recurrent Spontaneous Miscarriages in Jewish Women at High Risk for Breast/Ovarian Cancer

BRCA1/BRCA2 germline mutations are associated with an increased breast/ovarian cancer risk. Offspring gender ratios may be skewed against male births in BRCA1 mutation carriers. In addition, the lack of viable homozygous BRCA1/BRCA2-mutation carriers implies that recurrent miscarriages may be associ...

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Detalhes bibliográficos
Main Authors: Gal, Inbar, Sadetzki, Siegal, Gershoni-Baruch, Ruth, Oberman, Bernice, Carp, Howard, Papa, Moshe Z., Diestelman-Menachem, Tal, Eisenberg-Barzilai, Shlomit, Friedman, Eitan
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182091/
https://ncbi.nlm.nih.gov/pubmed/15116316
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