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4-Aminopyridine causes a voltage-dependent block of the transient outward K+ current in rat melanotrophs.

1. Whole-cell voltage-clamp recordings were made from acutely dissociated melanotrophs obtained from adult rats. 2. In the presence of external Na+ and Ca2+ channel blockers and 20 mM-tetraethylammonium (TEA) depolarizations to -40 mV or more evoked a fast-activating fast-inactivating outward K+ cur...

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Détails bibliographiques
Auteur principal: Kehl, S J
Format: Artigo
Langue:Inglês
Publié: 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181788/
https://ncbi.nlm.nih.gov/pubmed/2100315
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