An Envelope-Determined, pH-Independent Endocytic Route of Viral Entry Determines the Susceptibility of Human Immunodeficiency Virus Type 1 (HIV-1) and HIV-2 to Lv2 Restriction

We identified a postentry restriction, termed Lv2, which determines the cellular tropism of two related human immunodeficiency virus type 2 (HIV-2) isolates and is dependent on the sequence of the capsid (CA) and envelope (Env) proteins. To explain the reliance on both CA and Env, we proposed that r...

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Bibliographic Details
Main Authors: Marchant, David, Neil, Stuart J. D., Aubin, Keith, Schmitz, Christian, McKnight, Áine
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181606/
https://ncbi.nlm.nih.gov/pubmed/16014904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.15.9410-9418.2005
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