High-Potency Human Immunodeficiency Virus Vaccination Leads to Delayed and Reduced CD8(+) T-Cell Expansion but Improved Virus Control

CD8(+) T lymphocytes are thought to play an important role in the control of acute and chronic human immunodeficiency virus infections. However, there is a significant delay between infection and the first observed increase in virus-specific CD8(+) T-cell numbers. Prior to this time, viral kinetics...

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Main Authors: Davenport, Miles P., Zhang, Lei, Bagchi, Ansuman, Fridman, Arthur, Fu, Tong-Ming, Schleif, William, Shiver, John W., Ribeiro, Ruy M., Perelson, Alan S.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
主題:
Vaccines and Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181589/
https://ncbi.nlm.nih.gov/pubmed/16014966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.15.10059-10062.2005
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