Regulation of Matrix Metalloproteinase 9 Expression by Epstein-Barr Virus Nuclear Antigen 3C and the Suppressor of Metastasis Nm23-H1

Epstein-Barr virus latent protein EBNA3C has been shown to bind Nm23-H1, a known suppresser of cell migration and metastasis and a regulator of the guanine exchange factor Tiam-1. This interaction results in cellular translocation of Nm23-H1 to the nucleus and suppression of the antimigratory effect...

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Bibliographic Details
Main Authors: Kuppers, Daniel A., Lan, Ke, Knight, Jason S., Robertson, Erle S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181582/
https://ncbi.nlm.nih.gov/pubmed/16014933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.15.9714-9724.2005
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