Depression of a sustained calcium current by kainate in rat hippocampal neurones in vitro.

1. High-threshold, slow inactivating inward Ca2+ currents were studied in CA1 pyramidal neurones from rat hippocampal slices using the single-electrode voltage clamp technique. 2. Kainate (50-400 nM) induced a dose-dependent depression of the amplitude of the slow Ca2+ current. At a dose of 200 nM t...

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Bibliographic Details
Main Authors: Nistri, A, Cherubini, E
Format: Artigo
Language:Inglês
Published: 1991
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181471/
https://ncbi.nlm.nih.gov/pubmed/1770444
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