Organically modified silica nanoparticles: A nonviral vector for in vivo gene delivery and expression in the brain

This article reports on the application of organically modified silica (ORMOSIL) nanoparticles as a nonviral vector for efficient in vivo gene delivery. Highly monodispersed, stable aqueous suspension of nanoparticles, surface-functionalized with amino groups for binding of DNA, were prepared and ch...

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Detalhes bibliográficos
Main Authors: Bharali, Dhruba J., Klejbor, Ilona, Stachowiak, Ewa K., Dutta, Purnendu, Roy, Indrajit, Kaur, Navjot, Bergey, Earl J., Prasad, Paras N., Stachowiak, Michal K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181239/
https://ncbi.nlm.nih.gov/pubmed/16051701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504926102
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