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A stop codon polymorphism of Toll-like receptor 5 is associated with resistance to systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease with a complex genetic basis that includes susceptibility gene(s) within the chromosome 1q41–1q42 region. Toll-like receptor 5 (TLR5), the innate immune receptor for bacterial flagellin, maps to chromosome 1q41 and contains a common stop co...

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Autori principali: Hawn, Thomas R., Wu, Hui, Grossman, Jennifer M., Hahn, Bevra H., Tsao, Betty P., Aderem, Alan
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180760/
https://ncbi.nlm.nih.gov/pubmed/16027372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501165102
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