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Induction of transcription within chromosomal DNA loops flanked by MAR elements causes an association of loop DNA with the nuclear matrix

The spatial organization of an ∼170 kb region of human chromosome 19, including CD22 and GPR40–GPR43 genes, was studied using in situ hybridization of a set of cosmid and PAC probes with nuclear halos prepared from proliferating and differentiated HL60 cells. The whole region under study was found t...

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Detalhes bibliográficos
Main Authors: Iarovaia, Olga V., Akopov, Sergey B., Nikolaev, Lev G., Sverdlov, Eugene D., Razin, Sergey V.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180747/
https://ncbi.nlm.nih.gov/pubmed/16049024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki733
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