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Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload
Iron homeostasis plays a critical role in many physiological processes, notably synthesis of heme proteins. Dietary iron sensing and inflammation converge in the control of iron absorption and retention by regulating the expression of hepcidin, a regulator of the iron exporter ferroportin. Human mut...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1180556/ https://ncbi.nlm.nih.gov/pubmed/16075058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25683 |
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