Ordered-Subsets Linkage Analysis Detects Novel Alzheimer Disease Loci on Chromosomes 2q34 and 15q22

Alzheimer disease (AD) is a complex disorder characterized by a wide range, within and between families, of ages at onset of symptoms. Consideration of age at onset as a covariate in genetic-linkage studies may reduce genetic heterogeneity and increase statistical power. Ordered-subsets analysis inc...

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Main Authors: Scott, William K., Hauser, Elizabeth R., Schmechel, Donald E., Welsh-Bohmer, Kathleen A., Small, Gary W., Roses, Allen D., Saunders, Ann M., Gilbert, John R., Vance, Jeffery M., Haines, Jonathan L., Pericak-Vance, Margaret A.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Human Genetics 2003
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180484/
https://ncbi.nlm.nih.gov/pubmed/14564669
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