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CDC42 Is Required for Polarized Growth in Human Pathogen Candida albicans

Cdc42p is a member of the RAS superfamily of GTPases and plays an essential role in polarized growth in many eukaryotic cells. We cloned the Candida albicans CaCDC42 by functional complementation in Saccharomyces cerevisiae and analyzed its function in C. albicans. A double deletion of CaCDC42 was m...

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Autors principals: Ushinsky, Sophia C., Harcus, Doreen, Ash, Josee, Dignard, Daniel, Marcil, Anne, Morchhauser, Joachim, Thomas, David Y., Whiteway, Malcolm, Leberer, Ekkehard
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC118047/
https://ncbi.nlm.nih.gov/pubmed/12455975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.1.1.95-104.2002
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