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Inference on Haplotype Effects in Case-Control Studies Using Unphased Genotype Data

A variety of statistical methods exist for detecting haplotype-disease association through use of genetic data from a case-control study. Since such data often consist of unphased genotypes (resulting in haplotype ambiguity), such statistical methods typically apply the expectation-maximization (EM)...

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Bibliographic Details
Main Authors: Epstein, Michael P., Satten, Glen A.
Format: Artigo
Language:Inglês
Published: The American Society of Human Genetics 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180397/
https://ncbi.nlm.nih.gov/pubmed/14631556
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