Genetic Evidence for Interaction of the 5q31 Cytokine Locus and the CARD15 Gene in Crohn Disease

A common haplotype spanning 250 kb in the cytokine gene cluster on chromosome 5q31 has recently been reported to be strongly associated with Crohn disease (CD) in Canadian families. We have replicated this finding by both the transmission-disequilibrium test (TDT) (P=.016) and in a case-control asso...

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Autors principals: Mirza, Muddassar M., Fisher, Sheila A., King, Kathy, Cuthbert, Andrew P., Hampe, Jochen, Sanderson, Jeremy, Mansfield, John, Donaldson, Peter, Macpherson, Andrew J. S., Forbes, Alastair, Schreiber, Stefan, Lewis, Cathryn M., Mathew, Christopher G.
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Human Genetics 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180331/
https://ncbi.nlm.nih.gov/pubmed/12618963
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