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Two Modes of Germline Instability at Human Minisatellite MS1 (Locus D1S7): Complex Rearrangements and Paradoxical Hyperdeletion

Minisatellite MS1 (locus D1S7) is one of the most unstable minisatellites identified in humans. It is unusual in having a short repeat unit of 9 bp and in showing somatic instability in colorectal carcinomas, suggesting that mitotic replication or repair errors may contribute to repeat-DNA mutation....

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Bibliographische Detailangaben
Hauptverfasser: Berg, Ingrid, Neumann, Rita, Cederberg, Håkan, Rannug, Ulf, Jeffreys, Alec J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Human Genetics 2003
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180304/
https://ncbi.nlm.nih.gov/pubmed/12748906
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