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Cost-Effective Designs for Linkage Disequilibrium Mapping of Complex Traits

The current development of densely spaced collections of single nucleotide polymorphisms (SNPs) will lead to genomewide association studies for a wide range of diseases in many different populations. Determinations of the appropriate number of SNPs to genotype involve a balancing of power and cost....

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Bibliographic Details
Main Authors: Service, Susan K., Sandkuijl, Lodewijk A., Freimer, Nelson B.
Format: Artigo
Language:Inglês
Published: The American Society of Human Genetics 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180273/
https://ncbi.nlm.nih.gov/pubmed/12696019
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