SCA8 Repeat Expansion: Large CTA/CTG Repeat Alleles Are More Common in Ataxic Patients, Including Those with SCA6

We analyzed the SCA8 CTA/CTG repeat in a large group of Japanese subjects. The frequency of large alleles (85–399 CTA/CTG repeats) was 1.9% in spinocerebellar ataxia (SCA), 0.4% in Parkinson disease, 0.3% in Alzheimer disease, and 0% in a healthy control group; the frequency was significantly higher...

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Hlavní autoři: Izumi, Yuishin, Maruyama, Hirofumi, Oda, Masaya, Morino, Hiroyuki, Okada, Takayuki, Ito, Hidefumi, Sasaki, Iwao, Tanaka, Hiroyasu, Komure, Osamu, Udaka, Fukashi, Nakamura, Shigenobu, Kawakami, Hideshi
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Human Genetics 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180244/
https://ncbi.nlm.nih.gov/pubmed/12545428
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