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Extensive Linkage Disequilibrium, a Common 16.7-Kilobase Deletion, and Evidence of Balancing Selection in the Human Protocadherin α Cluster

Regions of extensive linkage disequilibrium (LD) appear to be a common feature of the human genome. However, the mechanisms that maintain these regions are unknown. In an effort to understand whether gene density contributes to LD, we determined the degree of promoter sequence variation in a large t...

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Bibliografiske detaljer
Main Authors: Noonan, James P., Li, Jun, Nguyen, Loan, Caoile, Chenier, Dickson, Mark, Grimwood, Jane, Schmutz, Jeremy, Feldman, Marcus W., Myers, Richard M.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Human Genetics 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180238/
https://ncbi.nlm.nih.gov/pubmed/12577201
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