Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells

Although ganglioside GD3 levels are highly elevated in malignant melanomas, the role of GD3 in melanomas' malignant properties has not been clearly shown. To investigate this problem, we genetically generated GD3-positive (GD3(+)) transfectant cells from a GD3-negative (GD3(-)) mutant line SK-M...

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Main Authors: Hamamura, Kazunori, Furukawa, Keiko, Hayashi, Takanori, Hattori, Takeshi, Nakano, Junji, Nakashima, Hideyuki, Okuda, Tetsuya, Mizutani, Hideki, Hattori, Hisashi, Ueda, Minoru, Urano, Takeshi, Lloyd, Kenneth O., Furukawa, Koichi
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180226/
https://ncbi.nlm.nih.gov/pubmed/16040804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503658102
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