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The metabolism of niacytin in the rat. Trigonelline as a major metabolite of niacytin in the urine

1. To investigate the fate of orally administered niacytin, urine and faeces of rats given single niacytin doses were examined for nicotinic acid derivatives methylated on the pyridine nitrogen atom, determined as trigonelline. 2. Methods were devised for the extraction of trigonelline from urine an...

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Bibliographic Details
Main Authors: Mason, J. B., Kodicek, E.
Format: Artigo
Language:Inglês
Published: 1970
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1179632/
https://ncbi.nlm.nih.gov/pubmed/5499964
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