Role of the Rab GTP-Binding Protein Ypt3 in the Fission Yeast Exocytic Pathway and Its Connection to Calcineurin Function

A genetic screen for mutations synthetically lethal with fission yeast calcineurin deletion led to the identification of Ypt3, a homolog of mammalian Rab11 GTP-binding protein. A mutant with the temperature-sensitive ypt3-i5 allele showed pleiotropic phenotypes such as defects in cytokinesis, cell w...

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Main Authors: Cheng, Hong, Sugiura, Reiko, Wu, Wenlian, Fujita, Masaaki, Lu, Yabin, Sio, Susie O., Kawai, Rena, Takegawa, Kaoru, Shuntoh, Hisato, Kuno, Takayoshi
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC117955/
https://ncbi.nlm.nih.gov/pubmed/12181359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-09-0463
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