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The metabolism in vitro and hepatic microsomal interactions of some enantiomeric drug substrates

1. The metabolism in vitro and microsomal interactions of (+)-amphetamine, (−)-amphetamine, (+)-benzphetamine and (−)-benzphetamine were studied with hepatic microsomes from phenobarbitone-pretreated male rabbits. 2. (+)-Benzphetamine was N-demethylated 30–35% faster than (−)-benzphetamine, but the...

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Detalhes bibliográficos
Main Authors: Hewick, David S., Fouts, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1179042/
https://ncbi.nlm.nih.gov/pubmed/4393781
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