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A linear equation that describes the steady-state kinetics of enzymes and subcellular particles interacting with tightly bound inhibitors
When an enzyme exhibits a high affinity for an inhibitor, the steady-state analysis of the mechanism is complicated by the non-linearity of normal dose–response plots or of reciprocal replots. It is shown here that dose–response measurements generate a linear plot of inhibitor concentration divided...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1972
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1178592/ https://ncbi.nlm.nih.gov/pubmed/4263188 |
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