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Phosphoric acid triester–glutathione alkyltransferase. A mechanism for the detoxification of dimethyl phosphate triesters

1. 2-Chloro-1-(2,4,5-trichlorophenyl)vinyl dimethyl phosphate (tetrachlorvinphos) is demethylated by mammalian liver supernatant (100000g) protein in the presence of GSH. 2. GSH acts as an acceptor of the transferred methyl group to form S-methyl glutathione. 3. The enzyme that catalyses this reacti...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Hutson, D. H., Pickering, B. A., Donninger, C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1972
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1178583/
https://ncbi.nlm.nih.gov/pubmed/5073748
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