C-reactive protein does not opsonize early apoptotic human neutrophils, but binds only membrane-permeable late apoptotic cells and has no effect on their phagocytosis by macrophages

BACKGROUND: It has been reported that C-reactive protein (CRP) binds both leukocyte FcγRIIA (CD32) and the plasma membrane of apoptotic cells. Since FcγRIIA becomes functionally enabled during neutrophil apoptosis, we sought to determine whether CRP bound to apoptotic neutrophils via FcγRIIA. METHOD...

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Detaylı Bibliyografya
Asıl Yazarlar: Hart, Simon P, Alexander, Karen M, MacCall, Shonna M, Dransfield, Ian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2005
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1177984/
https://ncbi.nlm.nih.gov/pubmed/15927062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-2-5
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