Decreased expression of the mannose 6- phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cells

BACKGROUND: Loss or mutation of the mannose 6-phosphate/insulin-like growth factor-II receptor (M6P/IGF2R) has been found in breast cancer. However, whether or not decreased levels of functional M6P/IGF2R directly contribute to the process of carcinogenesis needs to be further verified by functional...

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Bibliographic Details
Main Authors: Chen, Zhihong, Ge, Yinlin, Landman, Natalie, Kang, Jing X
Format: Artigo
Language:Inglês
Published: BioMed Central 2002
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC117795/
https://ncbi.nlm.nih.gov/pubmed/12149131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-2-18
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